In this post, I will look at the impact modifying mobile phase pH can have on reversed-phase separations.
Continue reading Using pH to optimize reversed-phase flash chromatography separations
Have you ever run flash column chromatography with mass detection (Flash-MS) and observed the total ion current or TIC increase during the purification only to find that there was no discernible compound contributing to the effect?
In this post I discuss how I came across this issue and the solution I found to work.
Continue reading How do I remove an annoying MS TIC background?
This article touches on the latest development in purification, ACI™ Accelerated Chromatographic Isolation, and how future needs of the typical Flash user will be met; way past the current limits of traditional flash. Flash evolved.
Continue reading Find Out Why The Era of Regular Flash Purification Has Come To An End
This article discusses two recent developments in flash purification that have increased cross-over with traditional HPLC techniques: cartridge media properties and new detectors in flash systems.
Continue reading The Lines Between Purification and Analysis are Blurring…