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SPE Columns and Plates

Biotage sample preparation column size table

ISOLUTE® SCX-3 is a strong cation exchange sorbent used to extract basic analytes from aqueous samples.

Structure of ISOLUTE SCX-3

ISOLUTE® SCX-3 is a ethylbenzenesulfonic acid bonded sorbent used for the extraction of basic compounds from aqueous (or partially aqueous) samples using a strong cation exchange retention mechanism. It keeps a permanent negative charge across the pH range. Analytes are eluted from ISOLUTE SCX-3 by eliminating the charge on the analyte (high pH), so this sorbent is not suitable for extraction of strong bases. The sorbent is supplied in the protonated form.  

ISOLUTE SCX-3 is the sorbent of choice when strong cation exchange with significant secondary non-polar interactions are required.

ISOLUTE SCX-3 is available in a wide range of SPE columns and 96-well plate formats.

ISOLUTE SCX-3 is also available as loose sorbent (100g pack).