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Biotage® Initiator+

Fourth Generation Microwave Synthesizer

356006 Biotage® Initiator+ Screen initiator+ with chemist Microwave Synthesizer initiator+ with vial microwave synthesizer vial orange liquid

Biotage® Initiator+ represents the latest in microwave synthesis performance. This instrument’s high-end specifications enable the chemist to explore new areas and perform the latest of innovations in chemistry. A reliable and upgradeable platform that allows chemists to make great discoveries in less time.


Rapid microwave-assisted organic synthesis for 
processing and method development

Press the large touch-screen and heat your organic reagents to 300 °C in just a few seconds. Biotage® Initiator+ does just that, and adds intelligent features that make innovation fast, reliable and safe.

Biotage® Initiator+ represents a new generation of synthesizer instruments for organic, medicinal, materials, nano and polymer chemistry professionals. It is an upgradeable and reliable platform allowing chemists to make great discoveries in less time.


Higher temperatures and pressures of up to 300 °C and 30 bar open new possibilities to perform difficult reactions. This allows for more flexibility in choosing a solvent. Even low boiling point solvents can now be run at higher temperatures. Using “Regulate on pressure” enables the reaction to reach highest possible temperature during the run. With the addition of the optional fiber optic probe, it is possible to measure the reaction temperature inside the vial for a higher degree of control.

Fully integrated computer

Load and run your samples using a touch screen for simple and intuitive navigation without the need for an external computer, keyboard or mouse. Results can be emailed directly to the user after a run, or downloaded through the USB port at the front of the instrument.

0.2 to 20 mL without system modifications

Use four different vial sizes in any order or combination at any time, without system modifications, for greater flexibility and direct scale-up of milligrams to grams.


Upgrade from a Biotage® Initiator+ by connecting the Biotage® SP Wave peptide synthesis module and the Robot Eight kit to perform microwave assisted peptide synthesis with vortex mixing to ensure homogeneous heat distribution.

Easy to operate

The large touch screen display provides an easy-to-use experience from set-up to results. By using the Biotage Wizard, the user is guided through the set-up of experiments step-by-step. It also includes assistance in converting conventional conditions to microwave synthesis parameters.


The reaction vessel is secured with a triple-tier safety lock to ensure maximum operator safety at all times. This in combination with high grade aluminum and a safe explosion box ensures maximum operator safety, even at high temperature and pressure.

Biotage® 1-Point Support™

Biotage’s world-class field service organization serves customers on site to provide the highest quality personalized support.