The Lines Between Purification and Analysis are Blurring…

This article discusses two recent developments in flash purification that have increased cross-over with traditional HPLC techniques: cartridge media properties and new detectors in flash systems.

Continue reading The Lines Between Purification and Analysis are Blurring…

Overcoming UV-Absorbing Mobile Phases

The UV absorption spectrum of some solvents overlaps with the product they dissolve, meaning that fraction collection processes cannot distinguish between solvent and product. The phenomenon, especially when applied to mobile phase gradients, can also result in drifting baselines and, in a worst case, swamp the sample out completely. Luckily, there is technology that solves this problem.

Continue reading Overcoming UV-Absorbing Mobile Phases